FPDHP, a novel anticancer agent, induces cell detachment and caspase-dependent apoptosis in Caki cells
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چکیده
منابع مشابه
FPDHP, a novel anticancer agent, induces cell detachment and caspase-dependent apoptosis in Caki cells.
The inhibition of topoisomerase can suppress the growth of cancer cells and induce apoptosis. The aim of this study was to evaluate the anticancer effects and mechanisms of action of a novel topoisomerase inhibitor, 4-(furan-2-yl)-2-(pyridin-2-yl)-5,6-dihydro-1,10-phenanthroline (FPDHP). FPDHP suppressed the growth of Caki, A549, HT29 and MDA-MB-231 cells, and induced caspase-dependent apoptosi...
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ژورنال
عنوان ژورنال: International Journal of Molecular Medicine
سال: 2014
ISSN: 1107-3756,1791-244X
DOI: 10.3892/ijmm.2014.1875